Molecular Diagnostics: A Revolution in Progress
نویسندگان
چکیده
منابع مشابه
Molecular diagnostics: a revolution in progress.
Molecular diagnostics now provides most laboratory tests in infectious disease and genetics, and an increasing number in oncology. Massively parallel methods allow sequencing of entire genomes, and sequence databases within and between species provide the information necessary to develop sensitive and specific diagnostic assays. Indeed, most microorganisms today are classified on the basis of s...
متن کاملNext-generation sequencing: a new revolution in molecular diagnostics?
In 1980, Fred Sanger and Walter Gilbert were awarded the Nobel Prize in Chemistry for discovering novel ways for sequencing nucleic acids. In 2003, the human genome sequence was published, an effort that involved more than 3000 scientists from 6 countries. The work took 13 years to complete, at a cost of nearly $3 billion. Only 6 years later, nucleic acid sequencing technologies have advanced t...
متن کاملOn the cusp of a revolution: melanoma molecular diagnostics.
‘‘New markers exist that correlate with melanoma progression, which may aid in melanoma identification, prognostication, and detection of minimal residual disease/early recurrence.’’ ‘‘We now understand that it is not sufficient to identify a tumor based on histology or the organ or origin as we have done traditionally but rather we now need to understand the particular molecular driver of the ...
متن کاملThe progress of molecular diagnostics of osteosarcoma.
Despite significant advances in the diagnosis and treatment of osteosarcoma in recent years, overall survival has remained low for over 2 decades. The standard diagnosis of osteosarcoma requires a combination of clinical presentation, radiologic studies, and pathologic tissue evaluation. A typical Codman's triangle in radiologic evaluation is vital in making correct diagnosis for middle or late...
متن کاملPrecision medicine, technologies, and molecular diagnostics
Introduction: Genetics, cellular and molecular medicines are cutting-edge sciences and technologies that play an important role in improving human health and quality of life. In addition, medical and biological sciences have clearly shown that the onset of diseases differs from person to person due to their different genetic profiles and variations in molecular basis. Therefore, it is feasible ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2015
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2014.233361